Animal and human studies with the mitochondria-targeted antioxidant MitoQ
Robin A.J. Smith1 and Michael P. Murphy 2
Ann. N.Y. Acad. Sci. 1201 (2010) 96-103
The Mitochondria-targeted ubiquinone MitoQ decreases ethanol-dependent micro and macro hepatosteatosis
Balu K Chacko, Victor Darley-Usmar et al
Hepatology (2011) in press
The mitochondria-targeted antioxidant MitoQ reduces metabolic syndrome but not atherosclerosis in ATM+/- / ApoE-/- mice
John R. Mercer, Antonio Vidal-Puig et al (2011)
American Heart Assoc. (in press)
Prevention of diabetic nephropathy in Inst2 +/-AkitaJ mice by the mitochondria-targeted therapy MitoQ
Balu K Chacko et al (2010)
Biochemical Journal 432. 9-19
Mitochondria-Targeted antioxidants as Therapies.
Robin Smith and Michael Murphy (2011)
Discovery Medicine (in press)
Mitochondria-Targeted Antioxidant MitoQ10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy
Delyth Graham, Anna F. Dominiczak et al (2009)
Hypertension ISSN: 1524-4563
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
Ariel C. Bulua, Richard M. Siegel et al (2011)
Journal of Experimental Medicine 10.1084/jem 20102049
Targeting Antioxidants to Mitochondria by Conjugation to Lipophilic Cations
Murphy MP, Smith RAJ.
Annu. Rev. Phamacol. Toxicol. 2007;47:629-56.
Available online at http://pharmtox.annualreviews.org/
Animal and human studies with the mitochondrial-targeted antioxidant MitoQ
Smith, RAJ and Murphy, MP (2010)
Ann.N.Y. Acad.Sci. ISSN 0077 - 8923
Non-alcoholic fatty liver disease: current concepts and management strategies.
Day CP.
Clinical Medicine, 2006; 6(1) 19-25
Nonalcoholic Fatty Liver Disease: A Review and Update
R. Lewis & R Mohanty
Dig. Dis. Sci. (2010) 55 560
The mitochondria-targeted anti-oxidant Mitoquinone decreases liver damage in a phase II study of hepatitis C patients
Edward J. Gane et al
Liver International (2010) ISSN 1478-3223
Mechanisms of Photoaging and Chronological Skin Aging
Fisher and Voorhees et al (2002)
Arch. Dermatol. 138 1462
Cellular response to infrared radiation involves retrograde mitochondrial signalling
Schroeder, Krutmann et al
Institut fur Umweltmedizinische Forschung (IUF) at the Heinrich-Heine-University Dusseldorf gGmbH, Auf’m Hennekamp 50, D-40225 Dusseldorf, Germany.
Free Radical Biology and Medicine (2007) 43 128 – 135
Report of an open study of Mitoquinol applied topically to prevent skin aging and photodamage
G.Fisher and J.Voorhees (2007) on file
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